@nixius
For removing grain DeGrainMedian(limitY=6,limitUV=8,mode=3) should be enough. I tried this script (nearly the same as J_Darnley's) and it works quite well too. With x264 and crf 20 (PS3 profile - HighProfile, subme6, RDO,...) I get around 700 kbit/s.
Code:
MPEG2Source("F:\SPLIT.d2v",idct=7)
Checkmate()
tfm(d2v="F:\SPLIT.d2v").tdecimate(mode=1)
Crop(8,0,-8,-0)
RemoveGrain(24)
DeGrainMedian(limitY=6,limitUV=8,mode=3)
#awarpsharp(depth=8,cm=1,blurlevel=1) #activate as you like (or try ToonLite)
gradfun2db(thr=1.6)