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lossless compression exists for your supposed reason...
low crf's as visually transparant as they are, still don't retain all the information like a lossless.
And then since you're encoding from an h.264 source file, you now have to worry about frame determinism, based on the decoder you're using and how you use it to make a new re-encode.
all in all, people use losslesses for the reason you state, not low crf encodes
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